The final section of The Baroque Cycle. Clever, detailed historical fiction epic about the 1600s and 1700s in Europe, The Middle East, and a bit of North Americas east coast. Interactions between fictional and real characters, without anything that can be proved didn't happen (like The Thee Musketeers). And, just a hint of magic. See Isaac Newton as a precocious Cambridge student probing the universe by maneuvering a darning needle through his eye; later, his occult obsessions.
Honorable mention to Children of Time and its sequel. Gripping sci-fi story about transforming, interactions between humans and computers, and other beings. Imaginative world about cultures very different from own own, and how they might evolve under different evolutionary conditions.
Also, honorable mention to Project Hail Mary.