I'm not sure these are actual problems (other than JS tooling, which I find opaque.) Instagram works just fine for the vast majority of people. It's taken as gospel that Javascript frameworks are "bloated" but 1) is this really true; and 2) if true does this really matter if the page loads fast enough? React is only 5.3kB and gives a very simple model for reasoning about code. Making code smaller or faster has a cost.
I'll also note that htmx is making a programming language, but they don't seem to understand they are making a programming language, and that usually ends up a disaster. See all the YAML stuff in the devops world.