*Top downloaded cask, which only includes GUI applications . Regular formulae are at [1]; the most popular is OpenSSL.
Note that these statistics are only for the last 30 days, and they only include users who have opted into Homebrew analytics (and I suspect users who don’t opt in are much less likely to download Microsoft products). That being said, I’m definitely still surprised that it’s number 1 — who uses Edge on a Mac? Maybe web developers who need to test their websites?