But saying "the more antivax deaths the better" just isn't OK. Those are human beings with parents, kids, siblings, extended families, and co-worker who may have made huge positive contributions to their communities and society.
Dehumanizing people isn't the answer. You can do better.
For example, one might argue that a prominent anti-vaxxer's lies convincing many people not to get the vaccine is extremely harmful; meanwhile the injection of reality by way of that anti-vaxxer's death could reverse some of that harm; and therefore hoping for high-profile anti-vaxxers to die in a high-profile way from the disease whose vaccine they decry is an ethical act.
Squinting a bit, we've just stumbled on something that looks a heck of a lot like a trolley problem! which of course is a famously difficult ethical dilemma with seemingly no good answer---or, at least, no one answer that satisfies everyone. Consequentialists might agree with the grandparent; deontologists would likely agree with you.
The point is: your "shame on you" response is not really engaging with the grandparent's argument, and is presupposing a not-entirely-uncontroversial view of ethics. Again, I'm not claiming right or wrong. The issue is that a "shame on you" argument has the effect, intentional or not, of obscuring your assumptions about the world and demonizing those who disagree with you.
So: perhaps you can do better, too?
Second, I'm fine engaging with the trolley problem on a conceptual / philosophical level. But based on the tone and content, it seemed the poster was happy that antivaxxers are dying: "for every antivax death, we get closer to 100% vaccination rate and finally get back to a normal life."
That's not a philosophical discussion about a real-world version of the trolley problem; that's hoping for more antivaxxer deaths so s/he can be happy.
After reflection on your post, I still think a gentle rebuke for the poster's very real schadenfreude is an appropriate response.
I feel a slight sadness for any early death, but even as a devoutly introverted person, I feel greater sadness for the years of social and family activities and living in fear of other humans. That's its own loss of living, even if it's not a loss of life.
If anyone wants to prove me wrong please do, I find my view of this extremely depressing.