I know of at least one tennis player who got a reaction which made him pause the season. World's top 73 Jeremy Chardy.
https://www.tennisworldusa.org/tennis/news/Tennis_Interviews...
There is definitely a risk there. Just unsure of the exact frequency, but this has been happening to athletes all around the world.
Where there's risk there should be choice and one should be able to weigh pros and cons.