You can move the region and thus move the mouse actually:

From: https://www.semicomplete.com/projects/keynav/

> The following is the default configuration:

    h : select the left half of the region
    j : select the bottom half of the region
    k : select the top half of the region
    l : select the right half of the region
    shift+h : move the region left
    shift+j : move the region down
    shift+k : move the region top
    shift+l : move the region right
    semicolon : Move the mouse to the center of the selected region
    spacebar : Move the mouse and left-click