DNS at the moment over 53/UDP is manageable and malleable. DNS over http is not and is up to your browser and hence a vendor.
Life on the helpdesk will become rather more nasty and worse than it is now and we probably won't get tools to diagnose what is going on inside the browser, and so life for IT will be increasingly crap.
I suggest we don't let the FAANGS run the world or the browser.