About 1) the solution for the FDA has been to ban flavorings, under the "think about the children" idea. While the risk of childen getting addicted to nicotine could be a concern, given the lack of measured risk, it could be as innocent as enjoying beer. About 2), nicotine seem to have negative effects on arteries and the skin mostly, causing premature aging (increase elastases and metalloproteases).
We may have more data in a generation or two, but it would be advisable to plan on reducing your use of e-cigs.
We know lungs are very sensitive and easily accumulate shit in them. Therefore the reasonable position is to assume that anything you point into your lungs is harmful, unless you have extremely strong evidence that it's not (as opposed to assume that something is safe until evidence that it's not.)
So: assume that e-cigs will give you lung cancer.