I see statements like this a lot, and I have to say they don't compute to me at all. They are eerily similar to the "cancel culture" conversation that comes up whenever someone quits out of their own volition.
Who is forcing your wife to shut down her day care, and how? If a subset of parents are uncomfortable sending their kids to day care for the foreseeable future, just tell them to come back when they're comfortable. Did your wife forget that it's her daycare?