What about binding of Isaac?
I've heard that noitka is pretty blendy
Minecraft launched a new genre
Auto chess is a new genre that came out recently
Binding of Isaak - action shooter
others I haven't seen. But I'm talking of different thing. What is absent in modern game are the attempts of synthesis of different genres, which were frequent in 80s or 90s, and gave us such gems as Dune 1 and Star Control 2.
Like Fallout 2? Check Atom RPG and Wasteland.
Like classic RPGs of 2000s? Check basically the entire 'Spiderweb Software' catalog.
Like Xcom? Check out Mutant: Year Zero
Metroidvania? There's a bunch (played Blasphemous recently, pretty good)
Zombies? Project zomboid
Pokemon? Monster Sanctuary
Lore you have to discover? Kenshi, Vagrus
Weird? Let's get weird: Library of Ruina
But to expand, Fallout 3 was nothing like Fallout 2 and neither was Fallout 4. We'll probably never get another Fallout title like F2, but we'll get indie games like it.
Same with pokemon, the last few (almost every?) pokemon game has essentially the same story, but Monster Sanctuary actually brings a new story to the table in a way Nintendo never will.
I also suspect that if someone were to do that today, reviewers would pan it for distracting from the main game or whatever. It's a different market, and more's the pity.
For example, in Crying Suns there are three kind of fighters you can deploy. A kills B, B kills C, C kills A. Does everything always boil down into this? It's just not fun. It's a lazy gaming trope.
In Bad North, every map is procedurally generated. It just gets old after the first few ones.
Having said that, I just don't have the time to really get into it again. And I don't have my best friend living in the same house with Ethernet cables strung between the rooms ;)
Can't you just connect 2 remote virtual machines with an EthernetOverIP channel and bring up IPX to play old games?