Paul DePodesta, the subject of the film Moneyball, actually spoke two days ago at the O'Reilly Strata (big data) conference in New York.

http://strataconf.com/summit2011/public/schedule/detail/2165...

So you can get his insights, straight from the horse's mouth, in a talk aimed at data geeks. For me, one of his main takeaway points was to question your assumptions. Always ask: "If we were to start again today, would we do things this way?" This exercise is used to tease out entrenched biases that you might not normally examine.

Because it was a keynote address, it should be publicly available on the O'Reilly youtube channel in the next few days, if not sooner: http://www.youtube.com/user/OreillyMedia#g/c/2543D0F253DD85C...