If anything, they might leave you wondering whether she was more trans than lesbian. Most of her protagonists are male and heterosexual (except for one of her last novels portraying a gay protagonist with aids). Women are portrayed like accessories rather than developed characters. I don't think she actually did any female protagonists at all. Tom Ripley's relationship with his spouse is definitely very cold (he has one from the second novel onwards) and weirdly a-sexual (e.g. they have separate bed rooms even).
There have been several movies based on the Tom Ripley novels that definitely portray him either as practically gay or at least very confused on that front. The Matt Damon one by Anthony Minghella is probably the most famous but arguably also the worst interpretation since it is all about guilt. There was one featuring John Malkovic loosely based on Ripley's Game that captured the cold psychopath a bit better and another one by Wim Wenders featuring Dennis Hoppers based on the same novel that had a very different spin on that. And there are a couple more obscure ones. Mostly those movies miss the main point of the character: he's egocentric, manipulative and ultimately sleeps like a baby without any guilt whatsoever once he's done murdering whoever stops him from that. All the tension in the books is about avoiding getting caught, which usually leads to additional victims. Not very compatible with the average Hollywood movie of course but it makes for an interesting anti hero.