Speaking of chassis, that makes offering different screen aspect ratios really hard, as you'll usually have a different sized/shaped chassis for a different aspect ratio. That might mean a different mainboard layout, different keyboard, different touchpad, and different battery, at least. That would vastly complicate Framework's offering, something I'm sure they're in no position to do as such a young company.
You can't change the CPU brand. Moving from Intel to AMD (or from the current Intel CPUs to a newer generation of Intel CPUs) would require an entirely different motherboard.
I used to be all in on the FOSS hardware train but at some point you just want to get some work done rather than debugging wifi drivers.