I've visited Germany and the UK a dozen or so times each, back in my international traveling consulting days. (Though only three times to Switzerland, for short visits - not enough to say much.)
German is not so difficult and many Germans speak English. I've had several English/non-German-speaking friends move there. And if your wife is working with a large company, they'll be able to help with the transition and government bureaucracy. Plus, she'll have plenty of co-workers who have done the same thing.
Germany also has good public services. There's more support for walkable/bikeable living than the UK.
Beyond that though really requires knowing more of your preferences. Friends of mine living in the UK didn't like sending their kids to gender-separated schools. I don't like the UK's privatization policies, nor its class system.
While my political and other persona views seem more aligned with German ones.
I can't help but wonder if, during those "international traveling consulting days", had a long-term contract in Germany, I might be living there now.