f.lux still lets me go to a lower colour temp than either Windows or OSX. I know I’m a niche audience, but it makes a difference to me and I don’t think I’ll get anywhere by shouting at the giant Wall of Apple to expand their range.
It's most likely just that I've conditioned myself, but in practice I don't really care about the cause. I only care that it helps me wind down in the evening.
There's something that feels good about being in sync with the natural day/night cycle. Cool white in the morning, warmer more dim light at night. I also like the idea of having a "sunrise/sunset" wall for any room that doesn't have proper windows but I've never implemented it.
Flux helped noticeably. For true relief FL-41 glasses would extend the time to a few hours.
A few times for late shifts in various businesses I've convinced the execs to shut off the fluorescents and I cannot describe the wave of relaxation that hits almost everyone.
It's so much worse also with the combo of 60Hz monitors and 60Hz AC power.
* is pure OTC saline -- not any of that other stuff people use for hangovers, etc.