Not sure if it still exists but there was a tool which let you mass block accounts. I've got no idea what you needed to do to end up on one of the lists that shipped with it - but it seemed rather sketchy. I'm also not sure what would motivate someone to spend time on such a thing; Twitter is already enough of an echo chamber.

Well, twitter (very fucking annoyingly) shows your tweets to people who don't follow you.

So you don't have to interact with people in any way to annoy them.

You don't need to interact with someone to get blocked, for instance, if I read discussion and saw people with facemasks, syringes, Ukrainian flag or emoji for other current trending thing I blocked these people, so I won't waste my time with reading their opinions in future and clean my experience at least from those obviously misguided people.

But that was before I left Twitter wasting my time, now I just passively read few accounts through Nitter, rarely opening Tweet discussion and not interacting in any way anymore. I plan soon to do same thing with Reddit, both of these are in the end just waste of time.