Genetic engineering is a distinctive and new technique for modifying the genomes of organisms, and the results of genetic engineering are referred to as GMOs.
The rhetorical flourish of decompiling the acronym and pretending it is descriptive rather than nominal does no one any favors. It's disingenuous, and doesn't alleviate someone's distrust of genetic engineering, because they know perfectly well that you know what they meant and are deflecting the conversation.