An application I have written recently for personal use is a double entry accounting system after GNUcash hosed itself and gave me a headache. This is based on Go and SQLite. The entire thing is one file (go embed rocks) and serves a simple http interface with a few JS functions like it is 2002 again. The back end is a proper relational model that is stored in one .db file. It is fully transactional with integrity checks. To run it you just start program and open a browser. To backup you just copy the .db file. You can run reports straight out of SQLite in a terminal if you want.
This whole concept could scale to tens of users fine for LOB applications and consume little memory or resources.