I think he was pretty clear that the Wolfram Institute, headed by Stephen Wolfram, has the single purpose of exploring the Wolfram Multicomputation model as a new foundation for all of science and mathematics. To do so, it is going to apply Wolfram's methods for productivity that have made Wolfram Research a successful company, and Wolfram Physics Project a successful delivery. Also of note, any major discoveries will be shared to the world in Wolframs clear and simple exposition style.

In short, maybe this leads somewhere, who knows, but right now it looks like a massive vanity project. It also looks like it has a good chance to start derailing other people's money from actual research into Wolfram Pet Theories.