I absolutely hate waste and was always proud of myself when I found ways to shave a thousand here and there off our AWS bill, but it was a bit depressing when I went through the thought exercise of "What would it be like for the company if I managed to get everything onto the AWS free tier?" And then compared that to what it would be like for the company if we found a way to make 1 or 2% more in revenue.
Early on, the math heavily favors worrying less about infra spend and more about product enhancements that can build revenue.
(Although often reducing the size of your infra for other reasons - usually around complexity for ops or ease of development can also have the side benefit of reducing cost and it seems worthwhile in those cases.)