I'm used to switching between Mac and PC layouts every day, but I personally prefer the Mac keyboard layout. Command is easier to press with a thumb compared to Ctrl, which requires the pinkie. Option allows you to input special characters with far more ease compared to any PC operating system (e.g Opt + Shift + - for an em-dash compared to some crazy incantation on Windows). Control is still available as an additional modifier if you want it.
A great side-effect of using Cmd as the primary modifier is that shortcuts inside your terminal become simplified. E.g Cmd + C to copy rather than Ctrl + Shift + C, or Cmd + T to open a new tab rather than Ctrl + Shift + T.
In an ideal world, Windows would switch to using the Win key as its primary modifier instead of Ctrl. That would make life so much simpler.