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Depends on the antidepressant, but SSRIs like Zoloft do suppress the effect. MAOIs, on the other hand, tend to increase the effect. I'm not sure about Wellbutrin.

There's some charts floating around about it on the internet: https://wiki.tripsit.me/wiki/Drug_combinations

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Be very, very careful about combining MAOI's with psychedelics (or other drugs).

Educate yourself thoroughly on what effect such combinations could have before you even think of doing this.

Combining drugs in general is often a very bad idea, and many overdoses and other adverse reactions have been due to this.

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