Ethereum is going deflationary. Not disinflationary like Bitcoin, but actually deflationary, with token burn. Whether you think deflationary money is bad or good is not germane to the problem I'm about to explain, as I see it.
Ethereum makes a claim at decentralization. However, by moving to a Proof of Stake system, they have set a fixed amount to be staked (32 ETH in this case, though the number itself does not matter). With the token going deflationary, that means that the opportunity cost to stake will always be increasing, mathematically, in ETH terms. The staking requirement does not adjust to changing token supply.
For argument's sake, if there are 100 ETH on the network, and you stake 1 ETH, you effectively need to lock away 1/100 of all wealth on the network. However, if 10 tokens get burned, now you lock away 1/90 wealth on the network. Staking that 1 ETH just got 10% more expensive because the opportunity cost of staking that ETH increased relative to spending it.
Economically, this means that the system is going to drive out marginal stakers, by design. The only response I have gotten from ETH holders is about staking pools, but staking pools don't fix the underlying economic incentive brought about by deflation: increasingly holders will find it less worthwhile to stake their ETH.
It seems to me that ETH is headed right for some kind of centralization death spiral, as only increasingly wealthier holders will be able to justify staking.