Or - a user follows a public figure out of good-faith interest, one of their tweets sparks controversy, and the replies get bad-faith violent (happens all the time). Then the next post is an ad for toothpaste. Colgate's not going to be happy to associate their product with vitriol.
Ultimately, YouTube users have a higher degree of control over what they consume, because they self select each video on a drop-by-drop level; on Twitter the user only curates which hoses they get blasted by. And we know that YouTube still struggles with ad suitability.