It is! At least 99%, in my experience. The one big difference is that Podman is "daemonless", which is actually a huge advantage in a lot of cases. The one downside is that it won't automatically restart your containers if your host machine reboots.
Once generated and enabled, your pods/containers act as systemd services that can be started, stopped etc.
[0]: https://docs.podman.io/en/latest/markdown/podman-generate-sy...
I reboot my machine after kernel updates and everything comes up flawlessly.
Looks like the service is called podman-restart.service on my system.