Just because bits are travelling across the wire and the digital artifacts happen to stored in Kalamazoo does not mean services or goods have crossed state lines. Otherwise, using a telephone to talk to your employee or customer in another state would involve crossing state lines. That simply isn't the case in the normal course of business.
The fact that this conversation is this complex gives me a feeling that remote work is going to be the backdrop for a lot of court cases in the next decade.