Aren't most physics equations approximate?
In practical terms, some of them are in the sense that it is impossible to measure their inaccuracy with common equipment and our primitive human senses. In the end, their purpose is to make predictions and help us make sense of what’s around us, they do not need to be exact.
We don’t know if they break down, because we have no means of measuring them more accurately on earth with all the statistical fluctuations happening.