I am aware of domain applications from F@H, but not core science work. What are those fundamental contributions?
Or did you mean something more fundamental, like "the biophysics of protein folding is primarily determined by entropic-driven hydrophobic collapse, not enthalpic contributions from hydrogen bonding?"
How was this demonstration done? Or are you referring to building a better high throughput screening mechanism? I'm by no means a protein expert, but I am trying to learn more about them.
>Or did you mean something more fundamental, like "the biophysics of protein folding is primarily determined by entropic-driven hydrophobic collapse, not enthalpic contributions from hydrogen bonding?"
I don't want to minimize anything or anyones work. But conformation of experimental observations via molecular dynamics simulation isn't what I was thinking of - but maybe I am misunderstanding your claim. Its my own ignorance.