Kind of. I picture it as being a function of input to output, so if the input changes, the output does too, but the output change is based on what changes have been made by the player.

E.g. if you have a hospital which can handle X patients per day and has a reputation of 90 when doing so, increasing the number of patients to 2x would probably decrease the reputation. You don't need to model the full hospital to determine this though, just have a "max patients" value which, when exceeded, puts a fractional multiplier on the output.