I've lived in the same spot in the mission for 10+ years (and been around longer), and other folks in the building for 20+: the mission hasn't regressed to the gang wars era (we have stories there...), but between the break-ins, homeless tents, poop & drugs, crazy people shouting at 4am, and occasional shootings, the neighborhood has slid back 10-15 years. Luckily I've only witnessed 1 murder, so the crime is merely 'costly and disruptive' vs 'life threatening', but that doesn't mean it's acceptable.
I lived in Seattle as well & visit frequently -- around when capital+pill hill gentrified again around MS downtown employees (games studios?): the current Amazon-era of the city is closer to SF 5-10 years ago vs today's slide back. It's not all good, to be clear: I'm guessing buying a place just got steadily harder as well, and families pushed further out.