There's no one change that, applied indiscriminately to an instrument, will reliably improve it. There are lots of things that work together to make a great instrument, and a great maker knows how to balance them.
(Side note: I'm also confident that there are instruments being made today that will equal Stradivari's given time enough. In my own experience, one viola made by Michael Darnton of Chicago was markedly better than any of the old Italian instruments I've played, though they were not of the first rank. That was an instrument fit for any use, and if I could have afforded it, I would never have let it go.)