I was really enjoying Obra Dinn until I took a break from it. A few weeks away, I simply couldn’t find my place in the story/puzzle/mystery and was too stuck to move on.
I also find I have to read books in one or two settings, I just loose the plot if it takes longer than that.
I've even seen games that explicitly say "you haven't loaded this save in a while. Do you want a refresher?"
It's a cool idea and seems to me to solve the problem of "where was I" after a break, but it hasn't caught on fully yet.