In an operating room or chip fab, the room would be over pressure and the new air coming into the room would be filtered. The cleanliness of that air would be determined by the quality of the filter.
Also, if you need air that clean, you need to have strategies for all sorts of things besides filtering.
The point is, you need to be very careful when you put numbers on the internet, and when you read numbers on the internet. Numbers make things feel more real than they are.
For me to actually trust the numbers here, I would need to see the graphs for multiple runs of each filter.
> The idea that the difference between 0.9005 and 0.90005 is "small" is … weird.
We aren't talking about a situation where both filters are processing all the air in the room. We're talking about a situation where the filters are only processing 10% of the air in the room. That's the defining characteristic of the hypothetical.
You're describing a situation where the filter is on the intake, but this thread and article are about purifiers within rooms. I agree that the math is really different in your situation.
The genuine HEPA filter in a cleanroom [0] is not sitting in front of a fan in the middle of the room. It’s very carefully installed such that all the air coming into the clean area goes through it once. The calculation is entirely different. (A medical or industrial HEPA filter may well be in the exhaust, in which case the considerations are again different.)
[0] There’s none of this “true HEPA” stuff in a cleanroom. There is a filter that meets a specific standard, and that filter will have a gasket that seals with considerable force against the air handling equipment. The “true HEPA” filter in a Wirecutter-approved air purifier achieves nowhere near 99.97% due to the lack of the aforementioned gasket regardless of how amazing the filter media may be.
Using one small number or produce another small number, so the difference looks small, doesn't hide the 10x change.