Does PyScript offer anything of significance over and above what Pyodide already offers, other than several py-* tags?
In my experience, it's trivial accomplish this with Pyodide.
Here's a web worker that hosts Pyodide and loads packages, PyPI wheels, external modules, etc. and launches type=text/python script tags in-browser:
https://github.com/h2oai/nitro/blob/main/web/public/nitride....
About ~100 lines of code.