Incidentally my first "true indie" game was SpaceChem. I'm tempted to play it again, maybe try and beat it this time. It's a very fun game, and cheap too, if you want to play along.
Glad they got to go out on their own terms. They're such a niche game studio that I was really worried that they closing their doors because of market apathy or dissatisfaction with the status quo. This is a good ending.