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Comment by ketamine | Hacker News Reader

Ketamine radically changed my life. I did it with a therapist. It allowed me to be completely objective about myself and my situations.

I am planning to visit oregon in 2023 so I can receive therapy with psilocybin which hopefully has less negative side effects.

Edit: typo

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I have a friend that is a therapist in CA that has been part of a Ketamine trial. The feedback was it can be remarkably successful. One of the "features" of this type of therapy is it something that happens as needed vs the daily pills that are standard now that can have serious issues.

Indeed. The research around glutamate / glutamine pathways seems very sound.

I did IV infusions which is nice because it can be stopped compared to IM injections, nasal spray or lozenges.

There is now a ketamine nasal therapy that is approved by most insurance plans for medication resistant depression. I’ve been going through the process, and will get my first dose in the coming weeks.

Thats great. I hope you get the outcome you desire!

Do you mean objective as opposed to subjective instead of objectionable? And what side effects did you have from therapy with ketamine?

Yes, thank you.

I do not like the numbness from the ketamine. I understand psilocybin is going to be a different experience that may not make me feel as out of control.

How long does the numbness from ketamine last? I never tried it and don’t need to, only have read about it, and numbness wasn’t one of them but I believe your account from your experience.

The heavy numbness ends about 10 minutes after the IV ends. I feel drunk and woozy / wobbly for about and hour to hour and a half and then just tired and weak and a little woozy for the next 4-6 hours.

That sounds like a manageable secondary effect. I imagined you feel numb for days or weeks after the treatment

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