Luckily, all the damage is already done, and our ecosystem is now well adapted to living in a bath of toxic gas.
Water is similar.
The essence of life is turning things into other things; doing so is difficult and dangerous.
That said everything would be more flammable.
It was actually before dinosaurs (Devonian and Cambrian Periods).
Analogously, there's nothing about the atmosphere preventing giant ground sloths from existing, but they nevertheless can't exist because they're not compatible with humans.
We don't know whether they would have coexisted with us. E.g., hippo population in Columbia is exploding. Megatherium sp. coexisted with hunter-gatherer humans for at least thousands of years.
Horses and camels can coexist with humans. They too were obliterated in the Americas by the comet strike.
But we anyway know people did hunt all of them, before that.