I think this Stanford course is aiming at a different goal than Harvard’s CS50. Harvard’s course seems to be aimed at people who are coders or want to be better at coding, so you learn about different languages, algorithms/data structures, SQL and such.

The Stanford course, especially the second half, appears to be more in the spirit of liberal arts. It covers high-level concepts in CS (server vs client, how does the internet work, what is encryption) that even someone who never writes code professionally will be able to use. They’ll be better able to read newspaper articles on tech topics, or perhaps more to the point, better equipped to be a PM/lawyer/BD in the tech space.