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Comment by aaaaaaaaaaab | Hacker News Reader

Bullshit. It has been known for decades that it's not the serotonin levels that matter, rather, the various down/upregulation cascades that follows after elevating serotonin levels for a few weeks. We don't know the specifics, but SSRIs work for a large chunk of people. That's beyond questioning at this point.

Can you attack the root cause by means other than serotonin levels? Possibly, but that's the best we have for now.

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The difference between SSRI's and placebo is surprisingly minimal.

Here's an interesting article laying out the issue at hand: https://connect.springerpub.com/content/sgrehpp/17/1/60

I know from first hand that SSRIs work.

Ah yes, anecdotal evidence, the bedrock of any sound scientific analysis.

The article posted that is being replied to isn't an intellectually honest attempt either.

You might have a point if the OP was the only one claiming this.

He isn't, and you don't.

Statement A: OP was the only one claiming this.

Statement B: you have a point

According to you, A => B.

However, you claiming (-A) does not necessarily mean -A => -B.

> OP was the only one claiming this.

He isn't. Not by many millions. "Anecdotal evidence" refers to one (or at least only a small number) of people claiming something.

Then OP, or you, should cite the study that shows this isn't anecdotal evidence. It does not fall to me to back up other people's points.

For you. That’s super great! I personally found them to drastically increase suicidal thoughts, impulses and actions!

do you have a non-paywalled link?

Not without resorting to SciHub, sadly. Here's someone's review, which provides a nice outline: https://medium.com/@lydiahosn/the-chemical-imbalance-hypothe...

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