I used to be obsessed with Tetris (both on the console and the 40 line clear version on the computer) and ended up programming a version of it that maps one key on the keyboard to one "slot/rotation" combination for each piece. Amazingly, there are enough keys to cover all of the combinations, so each drop is just one key press. Ended up getting some pretty good 40 line clear times for this weird version of Tetris; it felt like I was typing to play the game. I don't know if anyone has done something like that since then—that was probably a decade ago.