Huh? Famines, disease outbreaks and such were much more common at the beginning of the agricultural revolution. Hunter-gatherer bands were much safer from famine than early agricultural workers. This was true from the beginning, to the Irish famine in the UK 170 years ago. And insofar as epidemics - we are in at least one right now, if the monkey pox one doesn't get set to make two.
Insofar as general prosperity - the inflation-adjusted hourly wage in the US is below what it was a half century ago. This also pre-dates the recent inflation and Covid. I don't see how wages falling over the past 50 years is some sort of general prosperity.