Mean inflation from 2000-2021 (last year on record) was ~2.24%, including a 4.7% increase in 2021.[1]
$50k inflated at this rate would be approximately $80k.
I'm sure others are more qualified to discuss implications, but consider that while inflation erodes nominal purchasing power, it cannot account for effectively deflationary impacts of technology (for an example, see[2]). Of course, we cannot eat technology, at least not exactly; so we probably want to look at metrics related to how easy it is to live. It might be worth looking at cost per calorie, for example, or for commonly-available proxies (e.g., fast food prices).
[1] https://www.usinflationcalculator.com/inflation/historical-i...
[2] In 1999, hard drives were sized in the hundreds of megabytes and cost more than they do today. See, i.a., https://en.wikipedia.org/wiki/History_of_hard_disk_drives#20....