the only thing against it really is political nimbyism
Actually, from what I've read in the local newspapers in the areas affected, the politicians are all for it, so you're making assumptions there.
The people who are against it are the people who actually have to live with the stuff for the next thousand years.
If it's so safe, so stable, so easily rendered harmless, why not bury it in the bedrock beneath Manhattan, or Boston, or Virginia? All places that are far more geologically stable than, for example, Yucca Mountain.