In fact, Pinot Noir that is grown in Beaune (in Burgundy) talked about in this article is one of the oldest selections and might go back as far Roman times.
The Pinot Noir vines grown by the millions around the world are literally the same individual, cloned for probably 1200 years.
There are new grape varieties being bred all the time (including by myself), including ones with crosses with American Vitis species that are far better adapted for newer fungal pathogens and weather conditions. And not just bred, crosses (inter and intra specific) happen in the wild, too.
But in general they are not permitted in European viniculture, which is very conservative and has laws mandating specific varieties for specific regions, and even forbids genetics from "non-noble" species. In fact even when European breeding programs produce new varieties with inter-specific crosses, they still pretend to be "functionally" pure vinifera, just to get around laws written a century ago.