Look up Dr. Standfield on YouTube he has a great health channel on all this stuff and digs into everything including NMN/nr and all the backing metadata / Cochrane research papers…
"Molecules I Used To Take But Have Now Stopped
NMN:
I focus on stopping my NAD from declining by using Apigenin, Quercetin, Fisetin, Niacin, regular exercise, a great diet, periods of safe fasting, and restful sleep.
Since I’m 30, there’s not a reason for me to take NMN in addition to the above strategies at the moment.
As I enter my mid-30s, if my NAD levels are going down I will start taking NR.
At this stage, there is far more published human data on NR compared with NMN. NR also has its Generally Recognized As Safe (GRAS) certification from the FDA. For those reasons, I would start NR, and not NMN."
Since that Brad has stopped taking NMN and also requests people not to.
I had a one-on-one phone call with him Sunday (Dr. Standfield) and we discussed my experience with NMN vs NR and which was ideal for my situation. Long / short his review of my stack was summed up as ‘you are doing everything right stick with NMN.’ The only change was to switch from l-serine to glycine.
It is true Sinclair blocked him after he asked for clarion some of his research (so rude!).