I found asking for help as a junior is definitely harder when you don't have people around (walking up to someone's desk vs slack message with ~20-60 minute delay then zoom call): and I often found myself blocked on tasks.
I found learning is generally harder remotely for me as well: the sheer amount of information + resources + help you get from serendipitous conversations with other engineers should not be understated. It's the same reason people got so angry over paying so much for remote university: it is objectively a worse learning experience.
I think this is just my personal stance: but I think in my perfect world I work in office for the first 5-10 years of my career to optimize for learning + relationship building, and then once I get more senior (or have kids) I transition into either hybrid or fully remote.