I don't see how left and right hand matches the fact that there are 5x more 13-17 than 65 year old identifying as trans, unless you're suggesting that gender is learned, like right handedness was, and like all those older people, who should be trans, are now comfortable the way they are.
But, I'm nobody, looking at numbers I probably don't understand. The problem here is that Nature is saying that these numbers should be considered, but potentially discarded, depending on the conclusion they make.