Example: suppose I, a clueless tech guy, am negotiating with a savvy and aggressive money-guy. Assume for sake of argument we're raising $1 million, and my naive thoughts are that "The company is worth $5 million."
Me: "The company is worth $5 million."
Him: "We can totally work with a $5 million post-money valuation."
Me: "Great."
Almost everyone on HN knows I screwed myself. You think I just priced the company down to $4 million, right? Yeah, even worse.
Him: "So you know, it is customary for companies in Silicon Valley to make generous equity grants to attract and retain employees."
Me: "Oh totally."
Him: "The standard is 20%. You could get a lower number, but honestly, you'd look like a greedy bastard out to screw his employees, and our firm would probably not do business with you."
Me: "Oh, I am not greedy."
Him: "Great! So, $5 million post minus $1 million investment leaves $4 million Pre, reserving 20% of the post for employees, means you have $3 million in equity in this company."
Me: "Waitwaitwait, that sounds..."
Him: "That sounds like I just made you a millionaire. Son, you don't want to be unreasonable here. This is how business has always been done in the Valley. Besides, 100% of nothing is nothing. Don't worry about a bit of dilution, it happens, worry about that huge pile of money you'll have when you IPO."
Edit: I originally wrote it as 20% of the Pre, but checking with VentureHacks suggests that it would probably be calculated as 20% of the post. Easy to screw this stuff up, right? It's almost like it is designed that way...