I've extensively used: apt/dpkg (Debian and Ubuntu), rpm (Mandrake, Red Hat, Fedora), portage (Gentoo), and MacPorts. I also have some experience with package management on Void, Arch, and FreeBSD. I wanna say I used some unofficial package manager on BeOS back in the day, too, and I'm pretty sure QNX had one though I don't remember much about those.

HomeBrew is my favorite of them, overall. Though Portage is pretty damn great, for what it is.