I've setup mailu recently and can vouch for it's relative simplicity of setup and operation, including instructions for various of the verification types.

Hosting from home has been working for me, pending my network and homelab dramas. I haven't had trouble getting email to Microsoft or Gmail addresses

The caveat is that I don't self host my primary email address. I was going to be migrating it off Google, but they backed off enough to allow non-commercial gsuite users to remain free - and I don't want to close a door that I can't open again.

There is also iredmail: https://www.iredmail.org/

I have not used it, but might also be of interest:

https://modoboa.readthedocs.io/en/latest/index.html

I've also toyed with the idea of trying dbmail for a long time: https://dbmail.org/